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Probing the Peripheral Site of Human Butyrylcholinesterase

[Image: see text] Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) catalyze the hydrolysis of the neurotransmitter acetylcholine and, thereby, function as coregulators of cholinergic neurotransmission. For both enzymes, hydrolysis takes place near the bottom of a 20 Å deep active site g...

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Autori principali: Macdonald, Ian R., Martin, Earl, Rosenberry, Terrone L., Darvesh, Sultan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2012
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438789/
https://ncbi.nlm.nih.gov/pubmed/22901043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300955k
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