NEGATIVE EPISTASIS BETWEEN α(+) THALASSAEMIA AND SICKLE CELL TRAIT CAN EXPLAIN INTERPOPULATION VARIATION IN SOUTH ASIA

Recent studies in Kenya and Ghana have shown that individuals who inherit two malaria-protective genetic disorders of haemoglobin—α(+) thalassaemia and sickle cell trait—experience a much lower level of malaria protection than those who inherit sickle cell trait alone. We have previously demonstrate...

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Detalhes bibliográficos
Main Authors: Penman, Bridget S, Habib, Saman, Kanchan, Kanika, Gupta, Sunetra, Read, A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2011
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263337/
https://ncbi.nlm.nih.gov/pubmed/22133230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1558-5646.2011.01408.x
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