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Epistasis and the sensitivity of phenotypic screens for beta thalassaemia

Genetic disorders of haemoglobin, particularly the sickle cell diseases and the alpha and beta thalassaemias, are the commonest inherited disorders worldwide. The majority of affected births occur in low-income and lower-middle income countries. Screening programmes are a vital tool to counter these...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Penman, Bridget S, Gupta, Sunetra, Weatherall, David J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383351/
https://ncbi.nlm.nih.gov/pubmed/25521998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13241
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