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Anergic CD8(+) T Lymphocytes Have Impaired NF-κB Activation with Defects in p65 Phosphorylation and Acetylation
Because of the cytotoxic potential of CD8(+) T cells, maintenance of CD8(+) peripheral tolerance is extremely important. A major peripheral tolerance mechanism is the induction of anergy, a refractory state in which proliferation and IL-2 production are inhibited. We used a T cell receptor transgeni...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262885/ https://ncbi.nlm.nih.gov/pubmed/22205033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100793 |
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