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Induction of interleukin 12 responsiveness is impaired in anergic T lymphocytes

The cytokine, interleukin 12 (IL-12), stimulates both natural killer cells and T cells to proliferate and to secrete interferon gamma (IFN- gamma). The T cell proliferative response to IL-12 must be induced and is evident after T cell receptor-mediated stimulation. As reported here, tolerant CD4+ T...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191428/
https://ncbi.nlm.nih.gov/pubmed/7906705
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