Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation

Altered T cell function in systemic lupus erythematosus (SLE) is determined by various molecular and cellular abnormalities including increased IL-17 production. Recent evidence suggests a crucial role for signaling lymphocyte activation molecules (SLAMs) in the expression of autoimmunity. In this r...

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Main Authors: Chatterjee, Madhumouli, Rauen, Thomas, Kis-Toth, Katalin, Kyttaris, Vasileios C., Hedrich, Christian M., Terhorst, Cox, Tsokos, George C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262878/
https://ncbi.nlm.nih.gov/pubmed/22184727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102773
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