InsP(3) receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences

Orai1 proteins have been recently identified as subunits of SOCE (store-operated Ca(2+) entry) channels. In primary isolated PACs (pancreatic acinar cells), Orai1 showed remarkable co-localization and co-immunoprecipitation with all three subtypes of IP(3)Rs (InsP(3) receptors). The co-localization...

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Main Authors: Lur, Gyorgy, Sherwood, Mark W., Ebisui, Etsuko, Haynes, Lee, Feske, Stefan, Sutton, Robert, Burgoyne, Robert D., Mikoshiba, Katsuhiko, Petersen, Ole H., Tepikin, Alexei V.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262233/
https://ncbi.nlm.nih.gov/pubmed/21568942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110083
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