Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP(3) Receptors

Store-operated Ca(2+) entry is a ubiquitous mechanism that prevents the depletion of endoplasmic reticulum (ER) calcium [1]. A reduction of ER calcium triggers translocation of STIM proteins, which serve as calcium sensors in the ER, to subplasmalemmal puncta where they interact with and activate Or...

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Autors principals: Lur, Gyorgy, Haynes, Lee P., Prior, Ian A., Gerasimenko, Oleg V., Feske, Stefan, Petersen, Ole H., Burgoyne, Robert D., Tepikin, Alexei V.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887489/
https://ncbi.nlm.nih.gov/pubmed/19765991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.07.072
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