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Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca(2+) release through IP(3) receptors

Alcohol abuse is a major global health problem, but there is still much uncertainty about the mechanisms of action. So far, the effects of ethanol on ion channels in the plasma membrane have received the most attention. We have now investigated actions on intracellular calcium channels in pancreatic...

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Detalhes bibliográficos
Main Authors: Gerasimenko, Julia V., Lur, György, Ferdek, Pawel, Sherwood, Mark W., Ebisui, Etsuko, Tepikin, Alexei V., Mikoshiba, Katsuhiko, Petersen, Ole H., Gerasimenko, Oleg V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078340/
https://ncbi.nlm.nih.gov/pubmed/21436055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016534108
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