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Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells
The intracellular activation of trypsinogen, which is both pH- and calcium-dependent, is an important early step in the development of acute pancreatitis. The cellular compartment in which trypsinogen activation occurs currently is unknown. We therefore investigated the site of intracellular trypsin...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838486/ https://ncbi.nlm.nih.gov/pubmed/17363470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700951104 |
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