Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis

KEY POINTS: Giant trypsin‐containing endocytic vacuoles are formed in pancreatic acinar cells stimulated with inducers of acute pancreatitis. F‐actin envelops endocytic vacuoles and regulates their properties. Endocytic vacuoles can rupture and release their content into the cytosol of acinar cells....

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Chvanov, Michael, De Faveri, Francesca, Moore, Danielle, Sherwood, Mark W., Awais, Muhammad, Voronina, Svetlana, Sutton, Robert, Criddle, David N., Haynes, Lee, Tepikin, Alexei V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Molecular and cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023832/
https://ncbi.nlm.nih.gov/pubmed/29717784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275879
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