Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does not Reduce Severity of Experimental Acute Pancreatitis

Acute pancreatitis is a frequent disease that lacks specific drug treatment. Unravelling the molecular mechanisms of acute pancreatitis is essential for the development of new therapeutics. Several inducers of acute pancreatitis trigger sustained Ca(2+) increases in the cytosol and mitochondria of p...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Chvanov, Michael, Voronina, Svetlana, Zhang, Xiaoying, Telnova, Svetlana, Chard, Robert, Ouyang, Yulin, Armstrong, Jane, Tanton, Helen, Awais, Muhammad, Latawiec, Diane, Sutton, Robert, Criddle, David N., Tepikin, Alexei V.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349284/
https://ncbi.nlm.nih.gov/pubmed/32516955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061407
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