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Characterization of an O(2) Adduct of an Active Cobalt-Substituted Extradiol-Cleaving Catechol Dioxygenase

The first example for an O(2) adduct of an active Co-substituted oxygenase is observed in the extradiol ring cleavage of the electron-poor substrate 4-nitrocatechol (4NC) by Co(II)-homoprotocatechuate 2,3-dioxygenase (Co-HPCD). Upon O(2) binding to the high-spin Co(II) (S = 3/2) enzyme-substrate com...

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書誌詳細
主要な著者: Fielding, Andrew J., Lipscomb, John D., Que, Lawrence
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262093/
https://ncbi.nlm.nih.gov/pubmed/22175783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2095365
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