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Mechanism of extradiol aromatic ring-cleaving dioxygenases

The extradiol aromatic ring-cleaving dioxygenases activate molecular oxygen by binding both O(2) and the catecholic substrate to a reduced active site metal, generally Fe(II). Progress has been made in understanding the mechanism of this reaction through the combined use of kinetic, computational, b...

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Autor principal: Lipscomb, John D
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614828/
https://ncbi.nlm.nih.gov/pubmed/19007887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2008.11.001
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