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Directed Evolution of the Transcriptional Regulator DntR: Isolation of Mutants with Improved DNT-Response
The transcriptional regulator DntR, which previously has been isolated from bacterial strains capable of degrading 2,4-dinitrotoluene (DNT), was engineered in order to improve the ability to detect DNT. A directed evolution strategy was employed, where sequence diversity first was created by random...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261848/ https://ncbi.nlm.nih.gov/pubmed/22276138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029994 |
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