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The solution configurations of inactive and activated DntR have implications for the sliding dimer mechanism of LysR transcription factors

LysR Type Transcriptional Regulators (LTTRs) regulate basic metabolic pathways or virulence gene expression in prokaryotes. Evidence suggests that the activation of LTTRs involves a conformational change from an inactive compact apo- configuration that represses transcription to an active, expanded...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lerche, Michael, Dian, Cyril, Round, Adam, Lönneborg, Rosa, Brzezinski, Peter, Leonard, Gordon A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730206/
https://ncbi.nlm.nih.gov/pubmed/26817994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19988
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