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The solution configurations of inactive and activated DntR have implications for the sliding dimer mechanism of LysR transcription factors

LysR Type Transcriptional Regulators (LTTRs) regulate basic metabolic pathways or virulence gene expression in prokaryotes. Evidence suggests that the activation of LTTRs involves a conformational change from an inactive compact apo- configuration that represses transcription to an active, expanded...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Lerche, Michael, Dian, Cyril, Round, Adam, Lönneborg, Rosa, Brzezinski, Peter, Leonard, Gordon A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730206/
https://ncbi.nlm.nih.gov/pubmed/26817994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19988
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