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Directed evolution of a transcription factor PbrR to improve lead selectivity and reduce zinc interference through dual selection

Directed evolution has been proven as a powerful tool for developing proteins and strains with novel or enhanced features. In this study, a dual selection system was designed to tune the binding specificity of a transcription factor to a particular ligand with the ampicillin resistance gene amp (ON...

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Bibliografski detalji
Izdano u:AMB Express
Glavni autori: Jia, Xiaoqiang, Ma, Yubing, Bu, Rongrong, Zhao, Tingting, Wu, Kang
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148400/
https://ncbi.nlm.nih.gov/pubmed/32277291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01004-8
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