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Directed evolution of a transcription factor PbrR to improve lead selectivity and reduce zinc interference through dual selection
Directed evolution has been proven as a powerful tool for developing proteins and strains with novel or enhanced features. In this study, a dual selection system was designed to tune the binding specificity of a transcription factor to a particular ligand with the ampicillin resistance gene amp (ON...
Kaydedildi:
| Yayımlandı: | AMB Express |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer Berlin Heidelberg
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7148400/ https://ncbi.nlm.nih.gov/pubmed/32277291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01004-8 |
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