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Homologous Recombination Assay for Interstrand Cross-Link Repair
DNA interstrand cross-links (ICLs) covalently link both strands of the DNA duplex, impeding cellular processes like DNA replication. Homologous recombination (HR) is considered to be a major pathway for the repair of ICLs in mammalian cells as mutants for HR components are highly sensitive to DNA-da...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261721/ https://ncbi.nlm.nih.gov/pubmed/21660700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-129-1_16 |
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