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Homologous Recombination Assay for Interstrand Cross-Link Repair

DNA interstrand cross-links (ICLs) covalently link both strands of the DNA duplex, impeding cellular processes like DNA replication. Homologous recombination (HR) is considered to be a major pathway for the repair of ICLs in mammalian cells as mutants for HR components are highly sensitive to DNA-da...

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Detalhes bibliográficos
Main Authors: Nakanishi, Koji, Cavallo, Francesca, Brunet, Erika, Jasin, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261721/
https://ncbi.nlm.nih.gov/pubmed/21660700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-129-1_16
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