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Lifetime Cancer Risks in Individuals with Germline PTEN Mutations

PURPOSE: Age-adjusted cancer incidence and age-related penetrance studies have helped guide cancer risk assessment and management. PTEN Hamartoma-Tumor Syndrome (PHTS) is a term encompassing subsets of several clinical syndromes with germline mutations in the PTEN tumor suppressor gene. We conducted...

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Bibliographic Details
Main Authors: Tan, Min-Han, Mester, Jessica L., Ngeow, Joanne, Rybicki, Lisa A., Orloff, Mohammed S., Eng, Charis
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261579/
https://ncbi.nlm.nih.gov/pubmed/22252256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2283
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