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Frequent gastrointestinal polyps and colorectal adenocarcinomas in prospective series of PTEN mutation carriers
BACKGROUND & AIMS: Germline PTEN mutations cause Cowden syndrome (CS), associated with breast and thyroid cancers. Case reports found 35–85% of CS patients had gastrointestinal (GI) hamartomas. The association of benign and malignant GI neoplasias with CS remains debatable. Our goal is to descri...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652614/ https://ncbi.nlm.nih.gov/pubmed/20600018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.06.061 |
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