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Host Alloreactive Memory T Cells Influence Tolerance to Kidney Allografts in Nonhuman Primates

Transplant tolerance, defined as indefinite allograft survival without immunosuppression, has been regularly achieved in laboratory mice but not in nonhuman primates or humans. In contrast to laboratory mice, primates regularly have high frequencies of alloreactive memory T cells (TMEMs) before tran...

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Détails bibliographiques
Auteurs principaux: Nadazdin, Ognjenka, Boskovic, Svjetlan, Murakami, Toru, Tocco, Georges, Smith, Rex-Neal, Colvin, Robert B., Sachs, David H., Allan, James, Madsen, Joren C., Kawai, Tatsuo, Cosimi, A. Benedict, Benichou, Gilles
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261229/
https://ncbi.nlm.nih.gov/pubmed/21653831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002093
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