Host Alloreactive Memory T Cells Influence Tolerance to Kidney Allografts in Nonhuman Primates

Transplant tolerance, defined as indefinite allograft survival without immunosuppression, has been regularly achieved in laboratory mice but not in nonhuman primates or humans. In contrast to laboratory mice, primates regularly have high frequencies of alloreactive memory T cells (TMEMs) before tran...

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Main Authors: Nadazdin, Ognjenka, Boskovic, Svjetlan, Murakami, Toru, Tocco, Georges, Smith, Rex-Neal, Colvin, Robert B., Sachs, David H., Allan, James, Madsen, Joren C., Kawai, Tatsuo, Cosimi, A. Benedict, Benichou, Gilles
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261229/
https://ncbi.nlm.nih.gov/pubmed/21653831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002093
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