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Host Alloreactive Memory T Cells Influence Tolerance to Kidney Allografts in Nonhuman Primates
Transplant tolerance, defined as indefinite allograft survival without immunosuppression, has been regularly achieved in laboratory mice but not in nonhuman primates or humans. In contrast to laboratory mice, primates regularly have high frequencies of alloreactive memory T cells (TMEMs) before tran...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261229/ https://ncbi.nlm.nih.gov/pubmed/21653831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002093 |
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