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Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1
Precise regulation of Rag (recombination-activating gene) expression is crucial to prevent genomic instability caused by the generation of Rag-mediated DNA breaks. Although mechanisms of Rag activation have been well characterized, the mechanism by which Rag expression is down-regulated in early B c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260878/ https://ncbi.nlm.nih.gov/pubmed/22201127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110645 |
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