Učitavanje...
Insights into the oncogenic effects of PIK3CA mutations from the structure of p100α/p85α
Phosphatidylinositide-3-kinases (PI3K) initiate a number of signaling pathways by recruiting other kinases, such as Akt, to the plasma membrane. One of the isoforms, PI3Kα , is an oncogene frequently mutated in several cancer types. These mutations increase PI3K kinase activity, leading to increased...
Spremljeno u:
| Glavni autori: | , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260475/ https://ncbi.nlm.nih.gov/pubmed/18418043 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|