Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome

Down syndrome (DS) is the most common genetic cause of intellectual disability in children, and the number of adults with DS reaching old age is increasing. By the age of 40 years, virtually all people with DS have sufficient neuropathology for a postmortem diagnosis of Alzheimer disease (AD). Triso...

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Main Authors: Cenini, Giovanna, Dowling, Amy L.S., Beckett, Tina L., Barone, Eugenio, Mancuso, Cesare, Murphy, Michael Paul, LeVine, Harry, Lott, Ira T., Schmitt, Frederick A., Butterfield, D. Allan, Head, Elizabeth
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260028/
https://ncbi.nlm.nih.gov/pubmed/22009041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.10.001
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