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Targeting Artificial Transcription Factors to the Utrophin A Promoter: EFFECTS ON DYSTROPHIC PATHOLOGY AND MUSCLE FUNCTION
Duchenne muscular dystrophy is caused by a genetic defect in the dystrophin gene. The absence of dystrophin results in muscle fiber necrosis and regeneration, leading to progressive muscle fiber loss. Utrophin is a close analogue of dystrophin. A substantial, ectopic expression of utrophin in the ex...
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Autores principales: | , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
American Society for Biochemistry and Molecular Biology
2008
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259868/ https://ncbi.nlm.nih.gov/pubmed/18945675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804518200 |
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