Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via the ERK1/2 Signaling Pathway

Grb2-associated binder 1 (Gab1) coordinates various receptor tyrosine kinase signaling pathways. Although skeletal muscle differentiation is regulated by some growth factors, it remains elusive whether Gab1 coordinates myogenic signals. Here, we examined the molecular mechanism of insulin-like growt...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Koyama, Tatsuya, Nakaoka, Yoshikazu, Fujio, Yasushi, Hirota, Hisao, Nishida, Keigo, Sugiyama, Shoko, Okamoto, Kitaro, Yamauchi-Takihara, Keiko, Yoshimura, Michihiro, Mochizuki, Seibu, Hori, Masatsugu, Hirano, Toshio, Mochizuki, Naoki
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Molecular Basis of Cell and Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259763/
https://ncbi.nlm.nih.gov/pubmed/18577518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803907200
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires