Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling

Grb2-associated binder (Gab) family of scaffolding adaptor proteins coordinate signaling cascades downstream of growth factor and cytokine receptors. In the heart, among EGF family members, neuregulin-1β (NRG-1β, a paracrine factor produced from endothelium) induced remarkable tyrosine phosphorylati...

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Hlavní autoři: Nakaoka, Yoshikazu, Nishida, Keigo, Narimatsu, Masahiro, Kamiya, Atsunori, Minami, Takashi, Sawa, Hirofumi, Okawa, Katsuya, Fujio, Yasushi, Koyama, Tatsuya, Maeda, Makiko, Sone, Manami, Yamasaki, Satoru, Arai, Yuji, Koh, Gou Young, Kodama, Tatsuhiko, Hirota, Hisao, Otsu, Kinya, Hirano, Toshio, Mochizuki, Naoki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888569/
https://ncbi.nlm.nih.gov/pubmed/17571162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30651
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