Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via the ERK1/2 Signaling Pathway

Grb2-associated binder 1 (Gab1) coordinates various receptor tyrosine kinase signaling pathways. Although skeletal muscle differentiation is regulated by some growth factors, it remains elusive whether Gab1 coordinates myogenic signals. Here, we examined the molecular mechanism of insulin-like growt...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Koyama, Tatsuya, Nakaoka, Yoshikazu, Fujio, Yasushi, Hirota, Hisao, Nishida, Keigo, Sugiyama, Shoko, Okamoto, Kitaro, Yamauchi-Takihara, Keiko, Yoshimura, Michihiro, Mochizuki, Seibu, Hori, Masatsugu, Hirano, Toshio, Mochizuki, Naoki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Molecular Basis of Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259763/
https://ncbi.nlm.nih.gov/pubmed/18577518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803907200
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky