Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via the ERK1/2 Signaling Pathway

Grb2-associated binder 1 (Gab1) coordinates various receptor tyrosine kinase signaling pathways. Although skeletal muscle differentiation is regulated by some growth factors, it remains elusive whether Gab1 coordinates myogenic signals. Here, we examined the molecular mechanism of insulin-like growt...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Koyama, Tatsuya, Nakaoka, Yoshikazu, Fujio, Yasushi, Hirota, Hisao, Nishida, Keigo, Sugiyama, Shoko, Okamoto, Kitaro, Yamauchi-Takihara, Keiko, Yoshimura, Michihiro, Mochizuki, Seibu, Hori, Masatsugu, Hirano, Toshio, Mochizuki, Naoki
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2008
Предметы:
Molecular Basis of Cell and Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259763/
https://ncbi.nlm.nih.gov/pubmed/18577518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803907200
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы