Molecular Characterization of Striated Muscle-Specific Gab1 Isoform as a Critical Signal Transducer for Neuregulin-1/ErbB Signaling in Cardiomyocytes

Grb2-associated binder (Gab) docking proteins regulate signals downstream of a variety of growth factors and receptor tyrosine kinases. Neuregulin-1 (NRG-1), a member of epidermal growth factor family, plays a critical role for cardiomyocyte proliferation and prevention of heart failure via ErbB rec...

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Veröffentlicht in:PLoS One
Hauptverfasser: Yasui, Taku, Masaki, Takeshi, Arita, Yoh, Ishibashi, Tomohiko, Inagaki, Tadakatsu, Okazawa, Makoto, Oka, Toru, Shioyama, Wataru, Yamauchi-Takihara, Keiko, Komuro, Issei, Sakata, Yasushi, Nakaoka, Yoshikazu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115770/
https://ncbi.nlm.nih.gov/pubmed/27861634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166710
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