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Specifically alkylated DNA fragments. Synthesis and physical characterization of d[CGC(O(6)Me)GCG] and d[CGT(O(6)Me)GCG]
Two hexamer DNA fragments containing a carcinogenic modified base, O(6)-methyl guanine, have been synthesized by a solid-phase phosphotriester method, in which the unmodified guanine residues present were O(6) protected with the 4-nitrophenylethyl group. These two alkylated oligonucleotides were fou...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1983
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC325971/ https://ncbi.nlm.nih.gov/pubmed/6856460 |
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