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Specifically alkylated DNA fragments. Synthesis and physical characterization of d[CGC(O(6)Me)GCG] and d[CGT(O(6)Me)GCG]

Two hexamer DNA fragments containing a carcinogenic modified base, O(6)-methyl guanine, have been synthesized by a solid-phase phosphotriester method, in which the unmodified guanine residues present were O(6) protected with the 4-nitrophenylethyl group. These two alkylated oligonucleotides were fou...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kuzmich, Sandra, Marky, Luis A., Jones, Roger A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1983
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC325971/
https://ncbi.nlm.nih.gov/pubmed/6856460
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