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The effect of thalidomide on the pharmacokinetics of irinotecan and metabolites in advanced solid tumor patients
PURPOSE: Irinotecan and thalidomide are commonly administered antineoplastic drugs. Combination treatment may potentiate their antitumor effect and protect against irinotecan's intestinal toxicity. We investigated whether thalidomide can modulate the pharmacokinetics of irinotecan and metabolit...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259680/ https://ncbi.nlm.nih.gov/pubmed/21861128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-011-1727-4 |
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