Comprehensive Pharmacogenetic Analysis of Irinotecan Neutropenia and Pharmacokinetics

PURPOSE: We aim to identify genetic variation, in addition to the UGT1A1*28 polymorphism, that can explain the variability in irinotecan (CPT-11) pharmacokinetics and neutropenia in cancer patients. PATIENTS AND METHODS: Pharmacokinetic, genetic, and clinical data were obtained from 85 advanced canc...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Innocenti, Federico, Kroetz, Deanna L., Schuetz, Erin, Dolan, M. Eileen, Ramírez, Jacqueline, Relling, Mary, Chen, Peixian, Das, Soma, Rosner, Gary L., Ratain, Mark J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2009
Matèries:
Original Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690389/
https://ncbi.nlm.nih.gov/pubmed/19349540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.20.6300
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars