Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10

Por Ramírez, Jacqueline, Mirkov, Snezana, House, Larry K., Ratain, Mark J.
Publicado no Drug Metab Dispos (2015)

The effect of thalidomide on the pharmacokinetics of irinotecan and metabolites in advanced solid tumor patients

Por Ramírez, Jacqueline, Wu, Kehua, Janisch, Linda, Karrison, Theodore, House, Larry K., Innocenti, Federico, Cohen, Ezra E. W., Ratain, Mark J.
Publicado em 2011

Two Drug Interaction Studies of Sirolimus in Combination with Sorafenib or Sunitinib in Patients with Advanced Malignancies

Por Gangadhar, Tara C., Cohen, Ezra E. W., Wu, Kehua, Janisch, Linda, Geary, David, Kocherginsky, Masha, House, Larry K., Ramirez, Jackie, Undevia, Samir D., Maitland, Michael L., Fleming, Gini F., Ratain, Mark J.
Publicado em 2011

Dose-Finding and Pharmacokinetic Study to Optimize the Dosing of Irinotecan According to the UGT1A1 Genotype of Patients With Cancer

Por Innocenti, Federico, Schilsky, Richard L., Ramírez, Jacqueline, Janisch, Linda, Undevia, Samir, House, Larry K., Das, Soma, Wu, Kehua, Turcich, Michelle, Marsh, Robert, Karrison, Theodore, Maitland, Michael L., Salgia, Ravi, Ratain, Mark J.
Publicado em 2014

Sorafenib Dose Escalation is Not Uniformly Associated with Blood Pressure Elevations in Normotensive Patients with Advanced Malignancies

Por Karovic, Sanja, Wen, Yujia, Karrison, Theodore G., Bakris, George L., Levine, Matthew R., House, Larry K., Wu, Kehua, Thomeas, Vasiliki, Rudek, Michelle A., Wright, John J., Cohen, Ezra E.W., Fleming, Gini F., Ratain, Mark J., Maitland, Michael L.
Publicado em 2014