USP11 Stabilizes HPV-16E7 and Further Modulates the E7 Biological Activity

HPV-16E7 is a major transforming protein, which has been implicated in the development of cervical cancer. The stability of E7 is thus important to ensure its fully functional status. Using the yeast two-hybrid system, we found that USP11 (ubiquitin-specific protease 11), a member of a protein famil...

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Bibliographic Details
Main Authors: Lin, Ching-Hui, Chang, Hung-Shu, Yu, Winston C. Y.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259633/
https://ncbi.nlm.nih.gov/pubmed/18408009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708278200
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