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Kinetic Mechanism for Assembly of the m(7)GpppG·eIF4E·eIF4G Complex
Interaction of the mRNA cap with the translational machinery is a critical and early step in the initiation of protein synthesis. To better understand this process, we determined kinetic constants for the interaction of m(7)GpppG with human eIF4E by stopped-flow fluorescence quenching in the presenc...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533067/ https://ncbi.nlm.nih.gov/pubmed/18614538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801786200 |
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