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Smad7 Stabilizes β-Catenin Binding to E-cadherin Complex and Promotes Cell-Cell Adhesion

β-Catenin functions both as an adherens junction adhesion protein and as an essential mediator of the canonical Wnt signaling pathway. Wnts stabilize β-catenin and promote its accumulation in the nucleus, where it regulates transcription of the target genes. Here we show that Smad7 promotes cell-cel...

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Detalhes bibliográficos
Main Authors: Tang, Yi, Liu, Zhongyu, Zhao, Ling, Clemens, Thomas L., Cao, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527110/
https://ncbi.nlm.nih.gov/pubmed/18593713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800351200
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