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An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors
Intracellular protein aggregation is a common pathologic feature in neurodegenerative diseases such as Huntington' disease, amyotrophic lateral sclerosis and Parkinson' disease. Although progress towards understanding protein aggregation in vitro has been made, little of this knowledge has...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259017/ https://ncbi.nlm.nih.gov/pubmed/22052286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr500 |
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