लोड हो रहा है...
Phosphorylation of Profilin by ROCK1 Regulates Polyglutamine Aggregation
Y-27632, an inhibitor of the Rho-associated kinase ROCK, is a therapeutic lead for Huntington disease (HD). The downstream targets that mediate its inhibitory effects on huntingtin (Htt) aggregation and toxicity are unknown. We have identified profilin, a small actin-binding factor that also interac...
में बचाया:
| मुख्य लेखकों: | , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Microbiology (ASM)
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519718/ https://ncbi.nlm.nih.gov/pubmed/18573880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00079-08 |
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