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Role of HIF-1 and NF-κB Transcription Factors in the Modulation of Transferrin Receptor by Inflammatory and Anti-inflammatory Signals

Inflammation generates various changes in body iron homeostasis, including iron sequestration in the reticuloendothelial system with ensuing hypoferremia and anemia of chronic disease. Increased iron accumulation is caused by hepcidin-mediated down-regulation of the iron export protein ferroportin a...

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Detalhes bibliográficos
Main Authors: Tacchini, Lorenza, Gammella, Elena, De Ponti, Cristina, Recalcati, Stefania, Cairo, Gaetano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258948/
https://ncbi.nlm.nih.gov/pubmed/18519569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800365200
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