HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation.
Treatment with iron chelators mimics hypoxic induction of the hypoxia inducible factor (HIF-1) which activates transcription by binding to hypoxia responsive elements (HRE). We investigated whether HIF-1 is involved in transcriptional activation of the transferrin receptor (TfR), a membrane protein...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148697/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.21.4223 |
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