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HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation.

Treatment with iron chelators mimics hypoxic induction of the hypoxia inducible factor (HIF-1) which activates transcription by binding to hypoxia responsive elements (HRE). We investigated whether HIF-1 is involved in transcriptional activation of the transferrin receptor (TfR), a membrane protein...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Bianchi, L, Tacchini, L, Cairo, G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148697/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.21.4223
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