Unconventional endocytosis and trafficking of transferrin receptor induced by iron

The posttranslational regulation of transferrin receptor (TfR1) is largely unknown. We investigated whether iron availability affects TfR1 endocytic cycle and protein stability in HepG2 hepatoma cells exposed to ferric ammonium citrate (FAC). NH(4)Cl and bafilomycin A1, but not the proteasomal inhib...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Cell
Autori principali: Gammella, Elena, Lomoriello, Irene Schiano, Conte, Alexia, Freddi, Stefano, Alberghini, Alessandra, Poli, Maura, Sigismund, Sara, Cairo, Gaetano, Recalcati, Stefania
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2021
Soggetti:
Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120689/
https://ncbi.nlm.nih.gov/pubmed/33236955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-02-0129
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