Unconventional endocytosis and trafficking of transferrin receptor induced by iron

The posttranslational regulation of transferrin receptor (TfR1) is largely unknown. We investigated whether iron availability affects TfR1 endocytic cycle and protein stability in HepG2 hepatoma cells exposed to ferric ammonium citrate (FAC). NH(4)Cl and bafilomycin A1, but not the proteasomal inhib...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Gammella, Elena, Lomoriello, Irene Schiano, Conte, Alexia, Freddi, Stefano, Alberghini, Alessandra, Poli, Maura, Sigismund, Sara, Cairo, Gaetano, Recalcati, Stefania
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2021
Teme:
Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120689/
https://ncbi.nlm.nih.gov/pubmed/33236955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-02-0129
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