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Unconventional endocytosis and trafficking of transferrin receptor induced by iron

The posttranslational regulation of transferrin receptor (TfR1) is largely unknown. We investigated whether iron availability affects TfR1 endocytic cycle and protein stability in HepG2 hepatoma cells exposed to ferric ammonium citrate (FAC). NH(4)Cl and bafilomycin A1, but not the proteasomal inhib...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Biol Cell
Päätekijät: Gammella, Elena, Lomoriello, Irene Schiano, Conte, Alexia, Freddi, Stefano, Alberghini, Alessandra, Poli, Maura, Sigismund, Sara, Cairo, Gaetano, Recalcati, Stefania
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120689/
https://ncbi.nlm.nih.gov/pubmed/33236955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-02-0129
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