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Unconventional endocytosis and trafficking of transferrin receptor induced by iron

The posttranslational regulation of transferrin receptor (TfR1) is largely unknown. We investigated whether iron availability affects TfR1 endocytic cycle and protein stability in HepG2 hepatoma cells exposed to ferric ammonium citrate (FAC). NH(4)Cl and bafilomycin A1, but not the proteasomal inhib...

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Publicado en:Mol Biol Cell
Autores principales: Gammella, Elena, Lomoriello, Irene Schiano, Conte, Alexia, Freddi, Stefano, Alberghini, Alessandra, Poli, Maura, Sigismund, Sara, Cairo, Gaetano, Recalcati, Stefania
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120689/
https://ncbi.nlm.nih.gov/pubmed/33236955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-02-0129
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