Enzymatic Activity and Substrate Specificity of Mitogen-activated Protein Kinase p38α in Different Phosphorylation States

The mitogen-activated protein (MAP) kinases are essential signaling molecules that mediate many cellular effects of growth factors, cytokines, and stress stimuli. Full activation of the MAP kinases requires dual phosphorylation of the Thr and Tyr residues in the TXY motif of the activation loop by M...

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Bibliografiset tiedot
Päätekijät: Zhang, Yuan-Yuan, Mei, Zi-Qing, Wu, Jia-Wei, Wang, Zhi-Xin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2008
Aiheet:
Enzyme Catalysis and Regulation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258911/
https://ncbi.nlm.nih.gov/pubmed/18669639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801703200
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