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Enzymatic Activity and Substrate Specificity of Mitogen-activated Protein Kinase p38α in Different Phosphorylation States

The mitogen-activated protein (MAP) kinases are essential signaling molecules that mediate many cellular effects of growth factors, cytokines, and stress stimuli. Full activation of the MAP kinases requires dual phosphorylation of the Thr and Tyr residues in the TXY motif of the activation loop by M...

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Detalhes bibliográficos
Main Authors: Zhang, Yuan-Yuan, Mei, Zi-Qing, Wu, Jia-Wei, Wang, Zhi-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258911/
https://ncbi.nlm.nih.gov/pubmed/18669639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801703200
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