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The Mitochondrial Phosphate Carrier Interacts with Cyclophilin D and May Play a Key Role in the Permeability Transition

The mitochondrial permeability transition pore (MPTP) plays a key role in cell death, yet its molecular identity remains uncertain. Although knock-out studies have confirmed critical roles for both cyclophilin-D (CyP-D) and the adenine nucleotide translocase (ANT), given a strong enough stimulus MPT...

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Detalhes bibliográficos
Main Authors: Leung, Anna W. C., Varanyuwatana, Pinadda, Halestrap, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258905/
https://ncbi.nlm.nih.gov/pubmed/18667415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805235200
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